Case Report: Rectal Carcinoma Stage 3, age 69, Male

Partial surgical excision + chemo and radiation + fenbendazole

Fenbendazole Can Cure Cancer presents Case Reports of people who have treated their own cancers along with other articles to help understand how fenbendazole works. Previous articles covering other cancers are in the Archives link.

Colorectal cancer is the third most common cancer in the United States. The American Cancer Society’s estimates for the number of colorectal cancers in the United States for 2023 are:

• 106,970 new cases of colon cancer

• 46,050 new cases of rectal cancer

The rate of people being diagnosed with colon or rectal cancer each year has dropped overall since the mid-1980s, due to enhanced screened and life-style changes, according to the ACS. American Cancer Society data show that from 2011 to 2019, incidence rates for colorectal cancers dropped by about 1% each year. But this downward trend is mostly in older adults. In those younger than 50, rates have been increasing by 1% to 2% a year since the mid-1990s.

Overall, the lifetime risk of developing colorectal cancer is about 1 in 23 for men and 1 in 26 for women. However, each person's risk might be higher or lower than this, depending on their risk factors for colorectal cancer.

In the United States, colorectal cancer is the third leading cause of cancer-related deaths in both men and women. It's expected to cause about 52,550 deaths during 2023.

The following Case Report is from a reader who used fenbendazole to treat his stage 3 rectal cancer that had invaded the lymph nodes next to the rectum and some tissues outside of the rectal wall. This Case Report was initially submitted as a relatively detailed email message with more detailed follow-up answers to specific questions.

I was diagnosed with stage 3 rectal cancer in July of 2023 with a 5cm x 3cm tumor just above my anus along with an enlarged lymph node in my pelvic region measuring about 2 cm. The tumor had penetrated into the outer wall of the rectum and the pain and nerve irritation I was experiencing was significant.

Searched the internet and found the Tippens protocol and started about mid July with 450 mg/day of fenbendazole, 48 mg of ivermectin, 1200 mg of Curcumin twice/day, 1 Multivitamin & Vitamin D3 daily along with CBD oil at 24 ml per day (I've since switched to Olive Oil after reading about it on this blog). Started Chemo/Radiation for 6 weeks on 9/11 and had the first stack test done 3 weeks after treatment stopped, which was probably a little too soon to evaluate the effectiveness of the Chemo/Radiation. Radiation works in the body for about 6 weeks after treatment stops, according to the doctors treating me.

In addition, I had only been on the FenBen protocol for a little over 4 months at the time the stack tests were made. At any rate the tumor has shrunk significantly, to the extent the MRI reading referred to it as a scab and NED anywhere else in my body. My doctor still believes there may be something left of the tumor, and their protocol for this type of cancer is to administer first the chemo/radiation and afterwards, with chemo therapy. Something they are very proud of, since earlier methodology was to remove the anus after Chemo/radiation.

So, for the benefit of everyone involved, I've agreed to continue with the second phase of their protocol. (Hard to imagine this was the only option for people with my type of cancer 10 years ago.) I'm completely symptom free at this point in time, no blood and no irritation that I was experiencing prior to starting the protocol and Chemo/Radiation.

I'm feeling better than I have in some time and am quite confident the FenBen has helped shrink the enlarged lymph node and prevented any other metastasis from forming. I'll update my status as time goes by and would appreciate any feedback from others with similar condition.

W. M., Peoria, IL, December 29, 2023

Q: Any idea what may have caused your cancer? Genetics, environment, habits, lifestyle?
A: My mother was diagnosed with ovarian cancer (stage 4) at 68.  I was diagnosed at 69. My grandmother died of Hodgkin disease, so there was cancer on my mother's side. A genetic test was done to see if I had Lynch disease after my diagnosis, but no link was found. I was very active physically all my life and chose a career as a greenhouse owner first and later a grower/manager in the field. I spent 30 years in that industry, walking on average, a few miles/day around the large facilities I managed. I handled a lot of chemicals, from fertilizers to herbicides and insecticides. Some of which were incredibly deadly and over the years, removed from commercial use for safety and health reasons.

I changed careers and became, believe it or not, a CPA (found I really liked accounting after taking a few online courses). So, I gained weight and became quite sedentary which is the nature of the profession I chose. 

These circumstances certainly may have contributed to, or exacerbated my ultimately being diagnosed with cancer, but I tend to believe in my heart of hearts, that the ability of my body to recognize and destroy cancers diminished with age and also believe that was the case with my mother.

Q: What was your diagnosis? What prognosis did the doctors give you?
Q: In July of 2023, I went to see a surgeon to have what I thought at the time, a hemorrhoid ligated, based on the diagnosis of a local nurse practitioner I was seeing. He was an oncologist surgeon and after examination, told me I had cancer. I was officially diagnosed with rectal cancer, the tumor growing very close to my anus. He estimated that this slow growing type of tumor had been there for about 7 years.

The MRI revealed a tumor of about 5 cm in length and 2.5 cm in width. The outer wall of my rectum had been penetrated and an enlarged lymph node was also identified as possibly metastatic. I was diagnosed with stage 3C rectal cancer. The CAT scan was clean.

The history surrounding this type of cancer isn't good, but the doctor believed I had a good chance of defeating the disease but did not preclude the removal of my anus and installing a colostomy bag after treatment. In fact, this had been the standard for these types of cancers as early as 10 years ago. These days they apply Chemo/Radiation first to shrink the tumor and then chemotherapy only, for some months afterwards to hopefully destroy the tumor and any other possible malignancies that could be in the process of forming elsewhere  in the body. 

Q: What was your fenben protocol (dosage, frequency)?
A: After my diagnosis I immediately went home and started researching, ultimately finding Joe Tippens and his protocol.  I first purchased SafeGuard over the counter at a local Tractor Supply store, purchasing the 190 gm tube for equine, based on the cost/dose vs Panacur, which had become quite expensive locally. I purchased the application gun (a modified caulk gun) and a gram scale for weighing out the dose.  My daily protocol is:

• 450 mg/day of SafeGuard

• 2400 mg (two 1200 mg tablets) of UltraCur Curcumin

• 48 mg of ivermectin, purchased directly from Indian sources

• 1 multivitamin and 3 gel caps of Vitamin D3,

• 2 - 445 mg tablets of FenBen Med 

I take the fenbendazole with one tablespoon of olive oil. (I have switched from CBD oil to the olive oil after reading about research being done in Europe and the increased serum levels in the body from olive oil on this blog)

So, I'm actually taking about 1350 mg of Fenbendazole daily at this point in time. I found that some people were going even higher with the dosage with no discernable side effects, so I upped the dose from what Tippens recommends.

Q: What is your weight?
A: 205 lbs, 6’1”.

Q: What brand of fenbendazole did you use?
A: I purchased FenBen tablets and powder from two companies. 

I purchased FenBen powder (99% purity) from a company named FenLabs listed on Amazon that I have not used to date, because I was uncertain of the purity  This blog has stated that people are having success with the product, so I'm more confident of the product's efficacy now. 

The other is FenBen Med from Biotech Research and Development out of London, England. I've read a few reviews on this product from farmers who have had success with it on livestock and then this blog has also stated the same, so I'm confident this item is legitimate. I purchased the 445 mg tablets.

I guess you could say I sort of freaked out at first and looked for FenBen sources from other manufactures, purchasing what I could find, knowing this would be a lifetime discipline for me going forward but also because I wanted a very aggressive protocol initially until this cancer is gone. 

Q: When did you realize fenben was working? Did you start to feel better? Symptoms abate? Or did it require diagnostic testing for you to realize you were on the right track?
A: I decided to take Tippens's advice and use every means available to kill this monster. I finished 6 weeks of Chemo/Radiation in Early November and had my first stack tests done on Nov 28th. My feeling is that the testing should have been backed up a few weeks because we backed up the start date of the Chemo/Radiation until after my son visited in August of 2023. The hospital kept to the original schedule for the stack tests and as a result, the complete effects of the radiation were not included in the results. 

Nevertheless, the results were excellent, with the MRI radiologist calling what was left of the cancer a "scab". My doctor wanted to continue with the second phase of the treatment and was not as optimistic about the analysis after completing a sigmoidoscopy. He believes there is some cancer that is still alive even though the remnants of the tumor was in his words, "flat and brown". 

It took me about 3 weeks to recover from the effects of the radiation, which based on how I felt at the end of the treatment, was a miracle to me. And since then I have only continued to feel better. I have no symptoms of any kind that were present at the time of diagnosis. No pain, I now have regular stools, there are no electric shocks from the damage the tumor had done to my nerves in that area, there is absolutely no blood discharge and a there has been a dramatic increase in my energy and stamina. The increase in overall well being is something I've often read about from other users of the protocol, sometimes months before testing revealed the same. No Evidence of Disease.

I am still in the middle of this, so I'll update you with my results once I am tested again. I can tell you that I have no intention of doing anything more than this next round of Chemotherapy. There will be no surgery if the tumor is not completely gone in another few months. I believe that at worst, I can keep the tumor from increasing in size over time with the FenBen protocol. And that will be enough to allow me to live my life. 

Q: Did you have any issues or side-effects from the fenbendazole or anything else you were taking?
A: No.

Q: Did you tell your doctor about fenben, either while you were self-treating or afterwards?
A: I have not told my doctors about the protocol and likely will not. That's still up in the air, but based on the personalities, it seems it would be a waste of time and effort to engage them. We'll see.

Q: When you tell others about how fenben cured you do they believe you?
A: My family has had mixed reactions. My daughter was a nurse for many years and now works for a company that is repurposing drugs for application to treat diseases for which these drugs were not intended. She is very excited by the protocol I'm using. The rest of my family is happy I have no side effects from the protocol but otherwise thinks it’s a fantasy ambition of mine. My friends and some of my clients are open to what I'm doing and listen, but again like anything in life, you don't start really paying attention to alternatives until you are faced with reality. If I'm successful in my endeavors, they will likely contact me for more information if they end up with cancer. 

Summary

Congratulations to W. M. for taking the bull by the horns and doing everything within his power to attack his cancer. He is still in the early stages of the process but all signs look very encouraging for him to completely eradicate his cancer. And a huge Thank You! to W. M. for taking the time, and making the effort, to help others who may be similarly afflicted with his thoughtful and detailed information.

This Case Report is noteworthy for several reasons. First, the approach of attacking the cancer using multiple approaches. Surgery, traditional chemo and radiation, fenbendazole and ivermectin. All approaches made sense to him and he’s reaping the benefits of common sense combined with useful information.

Next is the dosing of fenbendazole. At 1350 mg per day this may seem high compared to the “standard” dose of 222 mg, but remember this 222 mg dose was simply carried over from the Panacur-C canine dewormer packet. There is no systematic parametric testing on the dose-response relationships between fenbendazole and cancer, so we all have to decide what amount is best for our specific cancers and circumstances. W. M. experienced no side effects from the 1350 mg per day dose of fenbendazole (and 48 mg daily dose of ivermectin) and his cancer was partially eradicated, which is the objective.

Next is the use of ivermectin, another repurposed drug, to fight his cancer. Ivermectin has an enormous safety profile, meaning that it appears safe to use in most contexts. We’ve touched on ivermectin in this Substack as an effective topical treatment for squamous cell carcinoma. Ivermectin has it’s own following in the alternative anti-cancer treatment space and we’ll wait for them to decode its secrets.

Next is the observation of the remnants of the tumor as a flat and brown scab. This description was noteworthy because there are other Case Reports, in various states of progress, involving rectal and anal cancers, that have stalled at this stage. The cancer appears eradicated according to all diagnostic measures, yet there remains a persistant imperfection in the tissue that demands attention by the oncologists. Whether the imperfection represents scar tissue, or something more serious, apparently is a mystery.

The focus of this Substack is fenbendazole. However, there is also great interest in the anti-cancer properties of ivermectin, another antiparasitic medicine. Dr. Paul Marik, one of the most highly acclaimed critical care researchers in the world based on the citations of his published papers*(h-index), recently released a book describing the merits of repurposed drugs like fenbendazole and ivermectin in the prevention and treatment of cancer. Marik rank ordered the value of dozens of anticancer substances reviewed with fenbendazole receiving the top Tier 1 designation along with “strong” recommendation based on available evidence. Interestingly, ivermectin received a Tier III designation citing “equivocal” evidence for it’s anti-cancer qualities. Based on the above Case Report results and many more to come, that designation will likely change in the near future. A link to Marik’s full free book is provided below, it is well worth reading.

References

Marik, P. E. (2023). The role of repurposed drugs and metabolic interventions in treating cancer

• The h-index is an author-level metric that measures both the productivity and citation impact of the publications, initially used for an individual scientist or scholar. The h-index correlates with success indicators such as winning the Nobel Prize, being accepted for research fellowships and holding positions at top universities. Marik enjoys an h-index of 105, among the highest in the world.

Items Included in All Posts

Fenbendazole vs. Mebendazole vs. Albendazole vs. Flubendazole: The benzimidazoles are very similar chemically and they have very similar mechanisms of action with respect to disrupting microtubule function, specifically defined as binding to the colchicine-sensitive site of the beta subunit of helminithic (parasite) tubulin thereby disrupting binding of that beta unit with the alpha unit of tubulin which blocks intracellular transport and glucose absorption (Guerini et al., 2019). If someone asks you how fenbendazole kills the cancer cells, the answer is in italics in the previous sentence.

The class of drugs known as benzimidazoles includes fenbendazole, mebendazole, albendazole and flubendazole. Mebendazole is the form that is approved for human use while fenbendazole is approved for veterinary use. The main difference is the cost. Mebendazole is expensive ~$555 per 100 mg pill, while fenbendazole is inexpensive ~48 cents per 222 mg free powder dose (Williams, 2019). As you may recall, albendazole is the form used to treat intestinal parasites in India and these cost 2 cents per pill. FYI, to illustrate how Americans are screwed by Big Pharma, two pills of mebendazole cost just $4 in the UK, 27 cents per 100 mg pill in India and $555 per 100 mg pill in the US.

While most of the pre-clinical research uses mebendazole, probably because it is the FDA-approved-for-humans form of fenbendazole, virtually all of the self-treating clinical reports involve the use of fenbendazole. Because the preclinical cancer studies use mebendazole (ironically the human form of fenbendazole) and humans self-treat their cancers with fenbendazole (the animal form of mebendazole) it is very reasonable to assume that mebendazole and fenbendazole are functional equivalents with respect to cancer. It would be helpful if future pre-clinical and clinical investigations simply used fenbendazole as a practical matter. For the purposes of this Substack, fenbendazole, mebendazole and albendazole are used interchangably.

Where to get fenbendazole
In our experience and the experiences of those that write in, it appears that the three readily available brands of fenbendazole (Panacur-C, FenBen Labs, Happy Healing Labs) are equally effective. Panacur-C can be obtained locally in pet stores, while they all can be obtained from Amazon.

If you would like to report your experiences with fenbendazole you can do so privately by email myfenbendazole@proton.me or more publically in the Comments section in any of the articles. Also, if you know of people who’ve tried fenbendazole, and it didn’t work, we’d be especially interested in hearing from you now. Understanding the conditions and factors that enhance or impede the success of fenbendazole in treating cancer are valuable.

Disclaimer:
Statements on this website have not been evaluated by the Food and Drug Administration. The contents of this website is for educational and informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis or treatment. This website does not provide any kind of health or medical advice of any kind. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. The case reports presented reflect the real-life experiences and opinions of other readers or users of the website. The experiences of those readers or users are personal to those particular readers/users and may not necessarily be representative of all readers/users. We do not claim, and you should not assume, that all other readers/users will have the same experiences. Do you own research, consult with relevant medical professionals before attempting to self-treat for any condition.